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China will produce fuel ethanol from biomass and coal

According to 135″, China will be able to produce a significant part of its fuel ethanol from biomass. Simultaneously, the production of fuel ethanol from coal has made significant process. The preferred route uses syngas which carbonylates dimethylester over a zeolite catalyst, providing methyl acetate, and simultaneously hydrogenates methyl acetate to ethanol over a Cu/ZnO catalyst. By 2018, Shaanxi Yanchang Group will have completed production facilities of 300.000 t following this route. Orient Securities analysts believe that biomass ethanol costs will be between 4700-5600 yuan/ton, whereas the cost of coal ethanol will be lower between 4000-4200 yuan/ton. China by the end of 2016 had proven coal reserves of 1.6 trillion tons.”

China Bio news release, September 22, 2017

One out of 4 Chinese molecular diagnostic companies are located in Beijing

According to the survey, 228 out of China’s present 1096 companies related to molecular diagnostics are located in Beijing. Among the leading companies are 1) Capital Bio, with approved products in in the field of genetic and infectious diseases, 2) Berry Genomics, with its Onconi tumor molecular diagnostic products based on high throughput sequencing, 3) Novogene Co., with a complete molecular pathology platform for tumor testing, 4) Lepu Gene Technology, with as a core platform on molecular diagnosis of cardiovascular diseases and high-throughput gene sequencing for personalized medicine, e. g., on CYP variations, 5) Annoroad Genomics, with a focus on reproductive health tests, 6) GeneCast Co., a company featuring genetic analysis of tumor markers, 7) SinoMDGene, with 23 CFDA-registered products covering tumor markers, drug-related personalized medicine and the detection of microbial pathogens, 8) iGene Tech Co., with independent target gene capture technology for tumor diagnosis etc., and 9) San Valley Co., with diagnostic products on the detection of solid tumors, blood cancer, genetic diseases, and prenatal diagnosis.

China Bio news release, September 21, 2017

YHD Co. introduces lysozyme-containing toothpaste Fe biological toothpaste””

The toothpaste was developed at Fudan University, and Fe in its name relates to Fudan enzyme”. It was tested since 2004 in various demonstration projects and finally approved in 2016. “Fe biological toothpaste” should not be rinsed with water for 2-3 minutes, in order to give full play to the antimicrobial function of lysozyme. YHD is a Chinese subsidiary of US WalMart.”

China Bio news release, September 20, 2017

China and Africa cooperate on anti-desertification program

CAS Xinjiang Institute of Ecology and Geography which has long-standing experience in desertification control and ecological restoration signed a memorandum with the the Panafrican Agency of the Great Green Wall (PAGGW) to support the African Great Green Wall initiativon by staff training and research of agro-sylvo-pastoral ecosystem monitoring and evaluation, as well as the development of a monitoring and evaluation system through a Geographic Information System and an Early Warning System.

CAS news release, September 20, 2017

China’s power generation from biomass will grow by over 30 % over 135″”

According to the 135 biomass energy development plan” released by the National Energy Board in December 2016, the installed capacity of China’s biomass power generation industry reached 15.33 million kwh in 2017. The average annual growth rate of the next five years (2017-2021) is planned for about 9.2%, thus in 2021, China’s biomass power installed capacity will reach 21.8 million kwh. Resources will be agricultural and forestry biomass, urban solid waste, biogas, bio-natural gas and bio-liquid fuel.”

China Bio news release, September 15, 2017

Chinese-German group develop conducting basalt fiber

A research group led by Prof. MA Pengcheng at CAS Xinjiang Technical Institute of Physics and Chemistry and Prof. Edith Mäder in the Leibniz Institute of Polymer Research Dresden in Germany utilized BF as a substrate to deposit/grow various carbon-based nanoparticles on fibre surface. The introduction of pyrolytic carbon (PyC) or carbon nanotubes (CNTs) on the surface of basalt fibers (BF) resulted in conducting BF. When a tow of this BF was embedded into a polymer matrix, the corresponding fibre-reinforced polymer showed a positive piezoresistance under mechanical deformation. The study was co-financed by the China-Germany Scientific Cooperation Program

CAS news release, September 13, 2017

Peking University Dental Hospital group develops personalized dental implants””

The group of TANG Zhihui is developing a method to replace extracted teeth by 3D-printed implants. In his approach, the tooth to be extracted is measured prior to surgery by dental cone beam computed tomography (CBCT), and the 3D data are synchronized with a 3D printer providing a copy of the original tooth including the root. After extraction of the original tooth, the printed dental implant is fixed to the alveolar bone by a metal nail through minimally invasive surgery. For the patient, the trauma is small, the repair time is short, and the cost is greatly reduced. TANG Zhihui’s team has completed the preclincial stage stage and observed no serious adverse reactions in animal experiments. The project will enter clinical trials this year, before mass production and application.

China Bio news release, September 13, 2017

China plans to build a rare diseases registration system by 2020

As to ZHANG Shuyang, vice president of Peking Union Medical College Hospital, by 2020 China will have included 59 types of orphan diseases into its registration system. At present, there are about 7,000 rare diseases recognized internationally, accounting for about 10% of human diseases. About 80% of rare diseases are believed to be due to genetic defects.

China Bio news release, September 11, 2017

China’s deep space exploration targets asteroids, Ganymede and Uranus beyond Mars

According to ZHANG Rongqiao, chief engineer at the Lunar Exploration and Space Engineering Centre under the China National Space Administration (CNSA), China’s roadmap for deep space exploration includes assembly of a space station in 2019, China’s Mars 2020 mission followed by a sample return mission around 2030, a visit to the Jupiter moon Ganymede in 1936, and to Uranus in 2040. Much of this program depends on the development of the Long March 9, a super-heavy-lift rocket in the same class as the Saturn V or NASA’s future SLSwill.

CAS news release, September 8, 2017

Central South University team starts clinical studies for type 1 diabetes xenotransplantation

The group of WANG Wei has announced that an expert review has cleared the way to study the effect of porcine Langerhans island extracts on type-1 diabetic human patients. The university center operates a pig breeding station, and the island extracts are obtained from newborn pigs whose immune system has been manipulated to contain each human patient’s own regulatory T-cells, thus preventing graft rejection. So far piglets imprinted with the immune system of 10 patients are under study, but the team prepares to treat ten thousands of patients every year in the future. The donor pigs have been selected from a race which is free of endogenous retrovirus C, a risk factor for human infection.

China Bio news release, September 8, 2017

China-US team stabilizes PLA by simple heating

A joint team of Jiangnan University in Wuxi and the University of Nebraska-Lincoln found that when PLA fiber is first heated to 200 C followed by slow cooling, the heat resistance of the resulting intertwined complex has improved to > 200 C, and structural integrity was maintained in hot water. It is hoped that this new technology could substitute for the more expensive procedure to polymerize mixtures of D- and L-lactic acid to scPLA.
https://www.eurekalert.org/pub_releases/2017-08/uon-tca083017.php

China Bio news release, September 9, 2017

Shenzhens’s Direct Genomics Co. introduces GenoCare genome sequencer

The machine is based on the Helicos technology, using sequencing by synthesis and detection of single-molecule fluorescence using total reflexion microscopy. In a test on E. coli genome sequencing where the GenoCare device was tested against Illumina’s MiSeq, reading accuracy of both instruments was comparable, but usable read length of the GenoCare was only 29 as compared to the MiSeq 146 bases. Direct Genomics plans to compensate this disadvantage by targeting specific genomic sequences by probes immobilized to the flow cell. This would qualify the instruments in particular for clinical tests such as non-invasive preimplantantation assays (NIPT) or of tumor-specific markers. Direct Genomics CEO Jiankui HE, backed by venture capital, claims to be able to build and sell 1000 units of GenoCare per year in China

China Bio, September 6, 2017

China’s State Council issues „Artificial Intelligence 2025“ plan

According to the plan, China will strive to achieve the world’s leading level by 2030 in artificial intelligence theory, technology and application, as the world’s major artificial intelligence innovation center. By 2025, the current status of robotics technology in Japan shall have been reached, including the largest number of IP. This plan is embedded in a „smart manufacturing 2025“ concept.

China Bio news release, September 4, 2017

China runs first tests at neutron beam spallation center in Dongguan, Guangdong Province

Neutron beams can examine subatomic materials without damaging their structure-an advance expected to lead to new discoveries in material science, clean energy and medicine. The China Spallation Neutron Source cost 1.87 billion yuan ($280 million) and took around six and a half years to build. It will be fully operational next year and Chinese scientists from more than 70 projects and 22 universities have applied to use it. The facility will also be open to foreign researchers.

CAS news release, Sept. 4, 2017

Team at CAS QIBEBT improves carbon capture by oleaginous microalgae through metabolic engineering

Using transcriptomic analysis, the group of XU Jian at CAS Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) observed a nuclear-encoded RuBisCO activase (nRCA) in Nannochlorpsis oceanica which functions as a mechanochemical motor protein and uses the energy from ATP hydrolysis to facilitate carbamylation and thus maintaining activity of RuBisCO by removing various inhibitors from RuBisCO catalytic sites. By overexpressing RCA, microalgal growth rate under air-level CO2 was enhanced by ~32%, biomass accumulation by ~46% and lipid productivity by ~41%, and photosynthesis by ~28%. Furthermore, abundance of RuBisCO large subunit protein increased by ~45%. 

CAS news release, September 4, 2017

A national biodegradable film evaluation test in agriculture sees advantages for polypropylene carbonate-based films

China is plagued by „white pollution“ originating from plastic residues, in particular for agricultural use. In 2015, the Ministry of Agriculture launched the National Biodegradable Film Evaluation Test” with more than 30 test sites, involving 8 crops. After 3 years of testing it was concluded that CAS Changchun Institute of Applied Chemistry’s biodegradable PPC film showed excellent functions concerning warming and moisture conservation at low production cost. 300.000 t of this carbon dioxide-based film were produced in April by Oriental New Chemical Co.”

China Bio news release, August 31, 2017

China speeds up drug development during “135”

According to a director of the National Health and Family Planning Commission, 95 % of patented drugs and 95 % of major medical equipment in China are still under patent protection from foreign companies. During the present 5 years plan (“135”), the government has taken steps to speed up drug development by Chinese companies, in particular by funding R&D, by improving the priority review system of CFDA and by revising patent regulations. 2018 is considered an excellent year for Chinese companies to obtain support for submitting original and proprietary new APIs.

China Bio news release, August 31, 2017

Bayer China to support 4 Chinese healthcare startups

Within its grants4apps program, https://www.grants4apps.com/shanghai/index_en.html, the company has selected 4 out of 130 start-up candidates for training and support. The startups are a) Tuo Xiao Intelligent, committed to the development of a home stethoscope and fetal heart rate monitor, b) Huiyun Tong, focused on a cloud-based, non-invasive diagnosis for coronary artery occlusion, c) Nuo Tong which develops intelligent medical robot equipment for the elderly, and d) Drop Technology, committed to the development of electronic antiperspirant patch products.

China Bio news release, August 30, 2017