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Targeted antibodies reduce symptoms of H7N9 infection in monkeys

The groups of SUN Shihui from Beijing Institute of Microbiology and Epidemiology and ZHAO Guangyu from Academy of Military Medical Science found that i.v. application of antibodies targeted against H7N9 reduced acute lung infection and systemic inflammation in infected African green monkey.

CAS news release, Jan. 20, 2015

Dongying, Shandong Province, opens first biomass pilot plant

The digester plant turns wheat and corn straw into 5 million m3 biogas per year and supplies nearby communities and CNG-based cars. Advanced biogas production technology from Germany allowed to overcome traditional shortcomings Engineering equipment design, modular standardized assembly, using intelligent control system, and reaction efficiency led to significantly increased gas production without odor and with zero emissions. The gas does not contain sulfur compounds and can be directly entered as a household fuel into the pipe network. The plant is operated by 山东宝力生物质能源股份有限公司.

China Bio news release, Jan. 29, 2015

China establishes “National Agricultural Technology Transfer Center”

The Center, located in Beijing, will include a National Agricultural technology Transfer trading platform”. The Center will organize and trade the country’s agricultural scientific and technological achievements. It will inform on and disseminate agricultural science and technology achievements and promote public information and trade.”

China Bio news release, Jan. 29, 2015

International Service for the Acquisition of Agri-biotech Applications (ISAAA) finds China No. 13 in global transgenic cultivation, mainly cotton and papaya

In Asia, China and India are still the main developing nations cultivating genetically modified crops. In 2014, cultivation of genetically modified crops were 3.9 million hectares. 2014 GM cotton adoption rate increased from 90% to 93%, while the anti-virus papaya acreage increased by about 50%. The production of food products from GM crops is hotly debated in China.

CAS news release, Jan. 29, 2015

Sino-American BioAtla Co. starts antibody production in Hefei, Anhui Province

According to BioAtla CEO Jai Short, therapeutic antibodies for various types of cancer treatment will be produced (30 % related to lung cancer), and the Hefei center will develop in the world’s largest center for antibody production, with about 100 target antibodies. Bioatla has operations in San Diego and Peking. The project is in cooperation with Peking University.

China Bio news release, Jan. 28, 2015

Group at Shanghai Institute of Organic Chemistry finds softer route to steroidal sapogenins

The team of Weisheng TIAN developed a process in the pilot scale which allows to oxidize sisal saponin to megestrol acetate using hydrogen peroxide instead of chrome oxide. China produces 4.000 t/a of saponins, about 90 % of the global production. The method was used to manufacture pregn-16-ene-20-one-3-ol acetate and other steroid drugs. Industrieller Partner ist Jiangsu Jiaerke Pharmaceuticals Co. in Changzhou.

China Bio news release, Jan. 28, 2015

Jilin Province issues ban on non-degradable plastic bags

Since January 1, Jilin Province banned the production and sales of non-degradable plastic bags and plastic cutlery. This is China’s first comprehensive plastic ban”. It is widely held that because biodegradable plastics do not have a price advantage, regulations will be difficult to succeed. Biodegradable plastic bags prices doubled in the meantime and prize will further restrict the use of consumers. The problem will be in the farmer’s market and in small business malls where no effective supervision can be done.”

China Bio news release, Jan. 19, 2015

CAS Wuhan Institute of Virology and others construct Mycobacterium tuberculosis proteome microarray

A team comprising the CAS Wuhan Institute of Virology, the CAS Institute of Biophysics, Shanghai Jiao Tong University, the Center for Tuberculosis Control of Guangdong Province, the CAS Institute of Hydrobiology, the Shanghai Municipal Center for Disease Control and Prevention, and TB Healthcare Biotechnology Co., Ltd., developed a proteome microarray with 4262 M. tuberculosis proteins, covering 95 % of this organisms proteome. It will be used for global analysis of protein-protein interactions between human immune cells and the MTB pathogen, for analysis of protein interactions with small molecules in the discovery of drug targets, and for high-throughput analysis of serum samples in the systematic discovery of biomarkers for use in the diagnosis of tuberculosis.

CAS news release, Jan. 19, 2015

CAS Institute of Genetics and Developmental Biology starts human tets on collagen complex to repair spinal cord injury

The clinical test will comprise 6 patients and is led by Jianwu DAI of this institute. The patients will be implanted mesenchymal stem cells and a collagen complex made up of collagen scaffold fibers, together with collagen binding brain-derived neurotrophic factor (BDNF). Previous tests on rats and dogs showed positive results. If successful, 20 – 30 more patients will be treated in the future.

CAS news release, Jan. 19, 2015

CAS Shanghai Institute of Organic Chemistry elucidates biosynthesis of lincomycin

China is the largest producer of lincomycin, a broad-spectrum antibiotic. The group around Wen LIU found that two bacterial thiols, MSH (mycothiol) and EGT(ergothioneine), couple during the biosynthesis of lincomycin A. EGT acts as a carrier to template the molecular assembly, and MSH is the sulfur donor for lincomycin maturation after thiol exchange

Qunfei ZHAO et al., Nature (2015) doi:10.1038/nature14137

Chinese team solves genome of Tibetan hulless barley

A group composed from scientists of CAS Chengdu Institute of Biology Research, Tibetian Scientists and BGI assembled 3,89 Gb or 87 % of the genome, of which over 80 % consists of repeats. Barley is an important ancestral species for many modern corn varieties.

CAS news release, Jan. 14, 2015

China builds 5th Antarctic research station

China’s Icebreaking research vessel Xuelong arrived near Victoria Land of Antarctica on Dec. 26, carrying 13 expedition members and 10 tons of supply. Targets are surveys, mapping and geo-information

CAS news release, Jan. 9. 2014

Hisun Biomaterials to become China’s largest producer of PLA

Hisun which produces already 50.000 t of PLA is starting construction of a new plant at Taizhou Bay on 313 acres, with an investment of 950 million Yuan. The construction period is given with 18 months.

China Bio news release, Jan. 9, 2015

Usun Bio Co., Jiangyin, offers mussel mucin as biological glue

The company, located in Jiangyin, Jiangsu Province, has developed mass production for a recombinant mussel peptide fused with RGD peptide which acts as a biological glue for wound healing, orthopedic applications etc. For technology development, CA Floudas, a Princeton scholar and member of the US Academy of Engineering, served as a consultant.

China Bio news release, Jan. 8, 2014