A team comprising the CAS Wuhan Institute of Virology, the CAS Institute of Biophysics, Shanghai Jiao Tong University, the Center for Tuberculosis Control of Guangdong Province, the CAS Institute of Hydrobiology, the Shanghai Municipal Center for Disease Control and Prevention, and TB Healthcare Biotechnology Co., Ltd., developed a proteome microarray with 4262 M. tuberculosis proteins, covering 95 % of this organisms proteome. It will be used for global analysis of protein-protein interactions between human immune cells and the MTB pathogen, for analysis of protein interactions with small molecules in the discovery of drug targets, and for high-throughput analysis of serum samples in the systematic discovery of biomarkers for use in the diagnosis of tuberculosis.

CAS news release, Jan. 19, 2015