“Morphology engineering” of Penicillium chrysogenum by RNA silencing of chitin synthase gene leads to enhanced penicillin production

A group at CAS Key Lab of Ion Beam Bioengineering, Hefei reports up to 41 % increase of penicillin production by mutants where class III chitin synthase was silenced

Hui LIU et al., Appl Microb. Biotech 10.1007/s00253-012-4581-3