A multi-center research team has cloned cathelicidin, a 29 amino acid peptide originally isolated from the skin of an indigenous frog which binds to bacterial lipopolysaccharides. It was found not only to inhibit bacterial growth, but also to stimulate the formation of anti-inflammatory cytokine release and be effective against sepsis
Lin WIE et al., Journal of Medicinal Chemistry DOI: 10.1021/jm4004158