Group at CAS Tianjin Institute of Industrial Biotechnology develops process for rare sugars based on pathway engineering of Corynebacterium glutamicum

By enhancing the formation of DHAP, introducing rhamnulose-1-phosphate aldolase (RhaD) and fructose-1-phosphatase (YqaB) obtained from Escherichia coli and deleting triose phosphate isomerase, 19.5 g/L of d-sorbose and 13.4 g/L of d-psicose were accumulated using a fed-batch culture mode

CAS news release, September 9, 2014