The researchers around Dunming ZHU designed variants of l-erythro-3,5-diaminohexanoate dehydrogenase from Candidatus Cloacamonas acidaminovorans (3,5-DAHDHcca) and uses β-keto acids, which were generated from β-keto-nitriles or β-keto-esters using nitrilase or lipase.

CAS news release, May 15, 2015