LI Ning and colleagues have developed a biomimetic route to synthesize pyromellitic acid from lignocellulose. Based on this reagent, a three-component cycloaddition reaction catalyzed by proline using formaldehyde, crotonaldehyde or acrylate/fumarate as raw materials led to 1,4-cyclohexanedimethanol (CHDM), 1,4-cyclohexanedicarboxylic acid (CHDA) or 1,2-cyclohexanedicarboxylate in yields of more than 70%.

CAS news release, April 28, 2018