About 78 percent of all studies about the relationship of gene and diseases are based on European individuals. Beijing Genomics Institute (BGI), one of the most prolific global DNA sequencing institutions located in Shenzhen, has now published a study on the genomes of 141,431 Chinese women generated for non-invasive prenatal testing (NIPT), mostly Han Chinese from China’s East coast. Features include that six genes display significant differences of Chinese people across latitudes, and people from the southern part of China have developed stronger immunity against malaria than those in the north, but a gene related to fatty acid metabolism has a much higher frequency in most of the northern provinces. In addition, people in Gansu and Qinghai provinces, a key area of the Silk Road, share more similar genes with Europeans.