In cooperation with CAS Guangzhou Institute of Biomedicine and Health, the group of JI Hongbin found by fate-mapping and clonbal analysis of BASCs that this cell type can become become activated by different lung injuries, and can differentiate into multiple cell lineages including club cells, ciliated cells, and alveolar type 1 and type 2 cells for lung regeneration. Thus BASCs show multipotency and self-renewal during lung repair and regeneration.
CAS news release, February 22, 2019