The group around LIU Yajun at the CAS Institute of Bioenergy and Bioproess Technology achieved directed engineering of cellulosome for in situ purification of the catalytic domain of Cel48S, an exoglucanase, in one step with high purity and full activity. Substantial biochemical and structural analyses based on native protein were performed subsequently to reveal the true features of this key cellulosomal enzyme.
CAS news release, February 12, 2018