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CAS Tianjin Institute of Industrial Biotechnology engineers carbonyl reductase for enantioselective reduction of ß-amino ketones

May 20, 2015

The team of Dunming ZHU has engineered a carbonyl reductase from Sporobolomyces salmonicolor to reduce several ß-amino ketones such as 3-(dimethylamino)-1-(2-thienyl)-propan-1-one, an important intermediate in antidepressant drugs, with over 90 % ee tot he R- or...

Baolingbao Co., a leader in functional sugars, improves isomaltooligosaccaride technology

May 20, 2015

The bioengineering company located in Yucheng, Shandong Province, is a leading enterprise for the production of functional sugars and polysaccharides. These are produced from plants as well as through enzyme and fermentation technology. Through cooperation with...

Giant Panda relies on bamboo food but harbors carnivore-like gut microbiota

May 20, 2015

As shown by Zhihe ZHANG, Director of the Chengdu Research Base of Giant Panda Breeding by 16S rRNA analysis of 121 fecal samples of 45 giant pandas throughout one year, the animals digest on average 12,5 kg of bamboo leaves and stems per day but have an extremely low...

CAS Chengdu Institute of Biology researchers develop olfactory alarm system based on trained mice

May 18, 2015

Researcher around Yuanye MA developed a novel apparatus designed to train water-deprived mice to detect odors using a go no-go system. With 1 % n-butanol as a test compound, 58 out of 59 mice delivered correct signals in real-time through a touch sensor. With 0.1 %...

Group at CAS Tianjin Institute of Industrial Microbiology establishes procedure for production of ß-amino acids

May 15, 2015

The researchers around Dunming ZHU designed variants of l-erythro-3,5-diaminohexanoate dehydrogenase from Candidatus Cloacamonas acidaminovorans (3,5-DAHDHcca) and uses β-keto acids, which were generated from β-keto-nitriles or β-keto-esters using nitrilase or lipase....
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